Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg Tablets$54.00
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Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg Tablets
SKU GME1110Antiviral
Product Introduction
Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg is a complete, three-medicine treatment for HIV-1 infection. It combines efavirenz with two nucleoside/nucleotide reverse-transcriptase inhibitors to control the virus and support immune function.
How to use
Take one tablet daily on an empty stomach, preferably at bedtime, at least one hour before or two hours after food. A bedtime routine can reduce the impact of dizziness or unusual dreams. Swallow the tablet whole and keep daily treatment uninterrupted.
How it works
Lamivudine and tenofovir disoproxil fumarate supply faulty building blocks that interrupt viral DNA production. Efavirenz binds reverse transcriptase at a different site and inhibits the same replication process by another mechanism.
Side effects
Dizziness, vivid dreams, sleep disturbance, headache, nausea, diarrhoea and rash can occur. Serious effects include severe skin reactions, psychiatric symptoms, liver injury and kidney or bone problems. Blistering rash, marked mood changes or persistent bone pain needs prompt assessment.
Important information
Baseline assessment includes hepatitis B, kidney function, liver tests and relevant mental-health history. Efavirenz interacts with several seizure medicines, antifungals and hormonal contraceptives. Stopping treatment can cause HIV rebound and, with HBV coinfection, a hepatitis flare.
Uses
- HIV-1 infection as a complete efavirenz-based antiretroviral regimen in patients suitable for the fixed-dose combination.
Benefits
The daily combination reduces HIV replication and supports preservation or recovery of CD4 cells. A single-tablet regimen reduces separate pill taking while providing medicines that act at complementary sites.
Why is bedtime often preferred for this combination?
Efavirenz can cause dizziness, impaired concentration and unusual dreams, particularly early in treatment. Taking the empty-stomach dose before sleep can make these effects less disruptive.
Are the 400mg and 600mg efavirenz combinations interchangeable?
They are different fixed-dose strengths. Changing between them changes efavirenz exposure, even when lamivudine and tenofovir amounts remain the same; it is a regimen change, not a tablet-for-tablet substitution.
Does a suppressed viral load mean HIV has been cured?
No. Suppression means the regimen is controlling replication. HIV persists in the body, so ongoing treatment is needed to maintain control.
Why can bone pain require kidney tests?
Tenofovir disoproxil fumarate can rarely cause kidney-tubule injury with phosphate loss and bone softening. Persistent bone pain or muscle weakness should not be dismissed as ordinary aches.
Reverse transcriptase: enzyme HIV uses to make DNA from RNA. NRTI: nucleoside/nucleotide reverse-transcriptase inhibitor. NNRTI: inhibitor binding reverse transcriptase at a separate site. CD4 count: measure of an important immune-cell population. Fanconi syndrome: kidney-tubule disorder causing loss of substances into urine.; AR: Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg أقراص; FR: Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg comprimés; PT: Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg comprimidos; ES: Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg comprimidos; RU: Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg таблетки; ID: Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg tablet; VI: Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg viên nén; MS: Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg tablet; TL: Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg tableta; ZH-SG: Lamivudine 300mg + Tenofovir Disoproxil Fumarate 300mg + Efavirenz 600mg 片剂