Glibenclamide 5mg + Metformin Hydrochloride 500mg Tablets

Product Introduction

Glibenclamide 5mg + Metformin Hydrochloride 500mg combines a sulfonylurea with metformin for type 2 diabetes when both increased insulin release and improved glucose handling are needed. It is an oral maintenance treatment alongside diet and physical activity.

How to use

Swallow the tablet with a meal and water. Keep meal times consistent and avoid skipping food after a dose, because glibenclamide can cause prolonged hypoglycaemia.

How it works

Glibenclamide stimulates insulin release from pancreatic beta cells. Metformin reduces liver glucose production and improves the response of tissues to insulin.

Side effects

Low glucose, nausea, diarrhoea, stomach discomfort and weight gain may occur. Confusion, collapse, persistent vomiting or unusual breathlessness needs urgent assessment.

Important information

Kidney or liver impairment can increase adverse effects, including prolonged hypoglycaemia. Dehydration, major surgery or contrast imaging can require temporary metformin interruption. Long-term use can lower vitamin B12.