Febuxostat 80mg Tablets$54.00
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Febuxostat 80mg Tablets
SKU GME926Product Introduction
Febuxostat 80mg is a urate-lowering medicine used for ongoing management of gout. It reduces the production of uric acid, helping limit the urate crystal deposits responsible for recurrent gout attacks and tophi.
How to use
Swallow with water at the same time each day, with or without food. Serum urate results guide dose adjustment. Continue established treatment through a gout flare unless a serious reaction occurs; a separate anti-inflammatory treatment may be needed for the flare.
How it works
Febuxostat inhibits xanthine oxidase, the enzyme involved in converting purines to uric acid. This lowers the supply of urate available to form crystals.
Side effects
Nausea, diarrhoea, headache, rash and abnormal liver tests can occur. Gout attacks may initially become more frequent. Blistering rash, jaundice, chest pain or sudden weakness requires urgent care.
Important information
Do not combine febuxostat with azathioprine or mercaptopurine because severe toxicity can result. Tell your doctor about heart disease, stroke, liver or kidney impairment, pregnancy and breastfeeding. Liver tests and cardiovascular history are important before and during treatment.
Uses
- Long-term urate lowering in gout associated with persistent hyperuricaemia.
Benefits
Maintaining a lower urate level can gradually reduce crystal burden and future gout flares. It does not provide immediate pain relief during an acute attack.
Why can gout worsen when febuxostat is first started?
Changes in urate levels can mobilise existing crystals and trigger early flares. Temporary flare-prevention treatment, often colchicine or an appropriate anti-inflammatory, may be included at the start.
Can I stop febuxostat once my joints are no longer painful?
Pain-free periods do not mean the urate problem has disappeared. Stopping ongoing treatment can allow uric acid to rise and crystal deposits to build up again.
Is febuxostat a painkiller for a sudden gout attack?
No. Its role is to reduce urate production over time. Acute redness, swelling and severe joint pain need a separate flare-management treatment.
How is the right febuxostat strength chosen?
The starting dose and later changes depend on the urate response, kidney and liver function and treatment history. A higher strength is not automatically needed because a flare is more painful.
Why is my heart history relevant to febuxostat?
Clinical studies have raised cardiovascular safety concerns in people with established cardiovascular disease. Previous heart attack, stroke or angina helps determine the most appropriate urate-lowering treatment.
Hyperuricaemia: an elevated blood urate level; Tophi: deposits of urate crystals under the skin or around joints; Xanthine oxidase: an enzyme involved in uric-acid production; Gout flare: an episode of acute inflammation caused by urate crystals; AR: Febuxostat 80mg أقراص; FR: Febuxostat 80mg comprimés; PT: Febuxostat 80mg comprimidos; ES: Febuxostat 80mg comprimidos; RU: Febuxostat 80mg таблетки; ID: Febuxostat 80mg tablet; VI: Febuxostat 80mg viên nén; MS: Febuxostat 80mg tablet; TL: Febuxostat 80mg tableta; ZH-SG: Febuxostat 80mg 片剂