Cefixime 50mg/5mL + Ofloxacin 50mg/5mL Oral Suspension

Cefixime with ofloxacin is a dual-antibiotic treatment for selected susceptible bacterial infections when a clinician judges the combination appropriate. It should not be used indiscriminately for uncomplicated diarrhoea or viral illness.
Reconstitute the suspension only with the specified water volume, shake before each dose and measure with an oral syringe. The amount per 5mL and the patient's weight determine the dose; use the stated in-use storage and discard period.
Cefixime inhibits bacterial cell-wall synthesis; ofloxacin inhibits DNA gyrase and topoisomerase IV, interfering with bacterial DNA replication.
Nausea, diarrhoea, abdominal discomfort, headache and dizziness may occur.
Tell your doctor about cephalosporin allergy, kidney disease, tendon problems, seizures and QT prolongation. Fluoroquinolones can cause serious tendon, nerve and neurological adverse effects.
Combines cell-wall and DNA-replication targets where the organism and clinical situation justify dual therapy.
No. Many cases are viral or self-limiting; treatment depends on the cause.
Stop the fluoroquinolone-containing treatment and contact the prescriber promptly; avoid stressing the painful tendon.
Yes. New nerve symptoms require prompt review because fluoroquinolone neuropathy can persist.
Leave at least two hours before or after iron, zinc, magnesium- or aluminium-containing antacids. These products can bind ofloxacin in the gut and reduce absorption.
No. Age, weight and the justification for a fluoroquinolone must be assessed.
Reduced renal clearance can increase exposure to either component.
Follow the prescribed duration unless adverse effects prompt a clinician-directed change.
Seek assessment for antibiotic-associated colitis instead of self-treating with antidiarrhoeals.
Cephalosporin: a beta-lactam antibiotic class. Fluoroquinolone: the antibiotic class containing ofloxacin. Susceptibility: whether a bacterium responds to an antibiotic., AR: Cefixime / + Ofloxacin / معلق فموي, FR: Cefixime / + Ofloxacin / buvable, PT: Cefixime / + Ofloxacin / suspensão oral, ES: Cefixime / + Ofloxacin / suspensión oral, RU: Cefixime / + Ofloxacin / суспензия для приёма внутрь, ID: Cefixime / + Ofloxacin / suspensi oral, VI: Cefixime / + Ofloxacin / hỗn dịch uống, MS: Cefixime / + Ofloxacin / suspensi oral, TL: Cefixime / + Ofloxacin / suspensiyong iniinom, ZH-SG: Cefixime / + Ofloxacin / 口服混悬液
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Cefixime 50mg/5mL + Ofloxacin 50mg/5mL Oral Suspension