Bisoprolol Fumarate 5mg + Hydrochlorothiazide 6.25mg Tablets

Product Introduction

Bisoprolol Fumarate 5mg + Hydrochlorothiazide 6.25mg is a beta-blocker and thiazide-diuretic combination for high blood pressure. It provides complementary treatment when reducing cardiac workload and increasing salt and water excretion are both useful for blood-pressure control.

How to use

Take the tablet once daily, preferably in the morning so increased urination is less likely to disturb sleep. It can be taken with or without food. Keep dosing regular and avoid suddenly stopping the beta-blocker component.

How it works

Bisoprolol blocks beta-1 receptors to slow the heart and reduce renin release. Hydrochlorothiazide reduces sodium reabsorption in the kidney's distal tubule, increasing salt and water excretion; its longer-term vascular effects also lower blood pressure.

Side effects

Dizziness, tiredness, slow pulse, thirst, increased urination and muscle cramps may occur. Sodium or potassium levels can fall, while uric acid and blood glucose can rise. Fainting, an irregular heartbeat, severe weakness or sudden eye pain with blurred vision need urgent assessment.

Important information

Tell your doctor about gout, diabetes, asthma, heart block, kidney or liver disease and previous sulfonamide reactions. Blood pressure, pulse, kidney function and electrolytes are followed during treatment. Lithium levels can rise with thiazides. NSAIDs may reduce blood-pressure control and worsen kidney function; hydrochlorothiazide also increases sun sensitivity.