Amantadine 100mg Tablets

Product Introduction

Amantadine 100mg is an antiparkinsonian medicine used for symptoms such as slowness, stiffness and tremor, and for selected medicine-induced movement symptoms. Its role differs from that of levodopa, although the medicines may be used together.

How to use

Take the conventional tablet with water, with or without food. If more than one daily dose is used, taking the later dose earlier in the day can reduce sleep disturbance. Kidney function determines the amount and interval. Reduce treatment gradually rather than stopping abruptly.

How it works

Amantadine modifies dopamine signalling and blocks NMDA-type glutamate receptors. These actions can improve motor symptoms and reduce excessive excitatory signalling in movement-control pathways.

Side effects

Dizziness, insomnia, nausea, dry mouth, ankle swelling and a mottled purple skin pattern can occur. Hallucinations, severe confusion, fainting or new compulsive behaviour need prompt assessment.

Important information

Drug accumulation is more likely with kidney impairment and in older adults. Tell your doctor about seizures, heart failure, hallucinations or glaucoma. Alcohol and sedating medicines can worsen confusion or dizziness. Sudden withdrawal may cause severe stiffness, fever or mental-state changes.