Alfuzosin 10mg + Dutasteride 0.5mg ER Tablets

Alfuzosin 10mg + Dutasteride 0.5mg combines an alpha-blocker with a 5-alpha-reductase inhibitor for urinary symptoms associated with an enlarged prostate. One component relaxes the bladder outlet while the other gradually reduces hormone-driven prostate enlargement.
Take the tablet after the same meal each day. Swallow it whole rather than crushing or chewing it. Improvement from muscle relaxation may occur sooner than the prostate-shrinking benefit, which develops over months.
Alfuzosin relaxes alpha-1-mediated smooth-muscle tone in the prostate and bladder neck. Dutasteride inhibits both types of 5-alpha-reductase, reducing dihydrotestosterone and gradually decreasing prostate volume.
Dizziness, headache, low blood pressure, reduced libido, erectile difficulty or altered ejaculation may occur. Fainting, a prolonged painful erection or a new breast lump needs medical assessment.
Dutasteride lowers PSA levels, so prostate-screening results need interpretation in the context of treatment. Pregnant women must not handle crushed or broken tablets because dutasteride can affect a male fetus. Mention liver disease, cataract surgery, other alpha-blockers and strong CYP3A4 inhibitors.
Combines earlier outlet relaxation with slower reduction in prostate size. In appropriate men with an enlarged prostate, long-term 5-alpha-reductase inhibition can reduce progression to retention or surgery.
Dutasteride changes hormone stimulation and prostate volume gradually. This is a different process from the quicker muscle relaxation produced by alfuzosin.
No. Dutasteride can substantially lower PSA even when cancer is present. The laboratory result must be compared with the treatment history and previous readings.
Yes. Reduced semen volume, ejaculatory changes, reduced libido or erectile difficulties can occur with this combination.
Blood donation is avoided during treatment and for six months after the last dose, to prevent exposure of a pregnant transfusion recipient to dutasteride.
Dihydrotestosterone: an androgen involved in prostate growth; 5-alpha-reductase: the enzyme converting testosterone to dihydrotestosterone; PSA: prostate-specific antigen measured in blood; Prostate volume: the size of the prostate gland; Combination therapy: treatment using medicines with complementary actions; AR: Alfuzosin 10mg + Dutasteride 0.5mg أقراص ممتدة التحرر; FR: Alfuzosin 10mg + Dutasteride 0.5mg comprimés à libération prolongée; PT: Alfuzosin 10mg + Dutasteride 0.5mg comprimidos de libertação prolongada; ES: Alfuzosin 10mg + Dutasteride 0.5mg comprimidos de liberación prolongada; RU: Alfuzosin 10mg + Dutasteride 0.5mg таблетки пролонгированного высвобождения; ID: Alfuzosin 10mg + Dutasteride 0.5mg tablet lepas lambat; VI: Alfuzosin 10mg + Dutasteride 0.5mg viên nén giải phóng kéo dài; MS: Alfuzosin 10mg + Dutasteride 0.5mg tablet pelepasan berpanjangan; TL: Alfuzosin 10mg + Dutasteride 0.5mg tabletang may pinalawig na paglabas; ZH-SG: Alfuzosin 10mg + Dutasteride 0.5mg 缓释片
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Alfuzosin 10mg + Dutasteride 0.5mg ER Tablets