Acyclovir 500mg Injection

Acyclovir 500mg is an intravenous antiviral used for serious herpes simplex and varicella-zoster infections. It is useful when the infection is severe or treatment by mouth is unsuitable.
The reconstituted dose is diluted and infused into a vein over at least one hour. Adequate hydration and kidney-based dose adjustment help limit crystal-related kidney injury.
Viral enzymes activate acyclovir in infected cells. The active form inhibits viral DNA polymerase and prevents herpes viruses from copying their DNA.
Nausea, vomiting and inflammation around the infusion site can occur. Kidney injury, confusion, tremor or seizures are important adverse effects, particularly with drug accumulation.
Kidney function and fluid balance are monitored during treatment. Acyclovir must not be given as a rapid intravenous bolus.
Provides reliable antiviral exposure for severe infection and can limit progression when started promptly.
No. It controls active viral replication but does not eliminate latent virus from nerve cells.
Acyclovir can crystallise in kidney tubules. Maintaining suitable hydration and a slow infusion reduces this risk.
Reduced kidney clearance can require a longer interval to prevent the medicine from accumulating.
New confusion, hallucinations, tremor or seizures can indicate toxicity, especially when kidney function is reduced.
Viral DNA polymerase: an enzyme viruses need to replicate. Encephalitis: inflammation of the brain. Latency: persistence of inactive virus in the body.; AR: Acyclovir 500mg حقن; FR: Acyclovir 500mg injection; PT: Acyclovir 500mg injeção; ES: Acyclovir 500mg inyección; RU: Acyclovir 500mg инъекция; ID: Acyclovir 500mg suntikan; VI: Acyclovir 500mg thuốc tiêm; MS: Acyclovir 500mg suntikan; TL: Acyclovir 500mg iniksyon; ZH-SG: Acyclovir 500mg 注射剂
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Acyclovir 500mg Injection