Acyclovir 250mg/10mL (25mg/mL) Injection$45.00
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Acyclovir 250mg/10mL (25mg/mL) Injection
SKU GME424Antiviral
Product Introduction
Acyclovir 250mg/10mL (25mg/mL) is an intravenous antiviral used for serious herpes simplex and varicella-zoster infections. It is useful when the infection is severe or treatment by mouth is unsuitable.
How to use
The required volume is further diluted and infused into a vein over at least one hour. The dose and interval depend on body weight, the infection being treated and kidney function.
How it works
Viral enzymes activate acyclovir in infected cells. The active form inhibits viral DNA polymerase and prevents herpes viruses from copying their DNA.
Side effects
Nausea, vomiting and inflammation around the infusion site can occur. Kidney injury, confusion, tremor or seizures are important adverse effects, particularly with drug accumulation.
Important information
Kidney function and fluid balance are monitored during treatment. Adequate hydration helps reduce the risk of acyclovir crystals forming in kidney tubules. Rapid intravenous bolus administration can increase kidney injury.
Uses
Severe herpes simplex infection, herpes encephalitis and serious varicella-zoster infection.
Benefits
Provides reliable antiviral exposure for severe infection and can limit progression when started promptly.
Does intravenous acyclovir remove dormant herpes virus?
No. It controls active viral replication but does not eliminate latent virus from nerve cells.
Why is hydration important?
Acyclovir can crystallise in kidney tubules. Maintaining suitable hydration and a slow infusion reduces this risk.
Why may the interval between infusions change?
Reduced kidney clearance can require a longer interval to prevent the medicine from accumulating.
What neurological symptoms need prompt attention?
New confusion, hallucinations, tremor or seizures can indicate toxicity, especially when kidney function is reduced.
Viral DNA polymerase: an enzyme viruses need to replicate. Encephalitis: inflammation of the brain. Latency: persistence of inactive virus in the body.; AR: Acyclovir 250mg حقن; FR: Acyclovir 250mg injection; PT: Acyclovir 250mg injeção; ES: Acyclovir 250mg inyección; RU: Acyclovir 250mg инъекция; ID: Acyclovir 250mg suntikan; VI: Acyclovir 250mg thuốc tiêm; MS: Acyclovir 250mg suntikan; TL: Acyclovir 250mg iniksyon; ZH-SG: Acyclovir 250mg 注射剂