Estradiol 0.06% Gel

Product Introduction

Estradiol 0.06% Gel, 80 g is a topical estrogen hormone-replacement therapy used for menopausal symptoms linked to estrogen deficiency, such as hot flushes and vaginal or vulvar dryness, burning, or itching. Estradiol gel delivers estrogen through the skin into the bloodstream. Estrogen therapy is not for preventing heart disease or dementia, and risk assessment matters before starting. People with a uterus may need a progestogen to reduce endometrial cancer risk from unopposed estrogen.

How to use

Apply Estradiol 0.06% Gel, 80 g exactly as prescribed to the recommended clean, dry skin area. Let it dry before dressing, wash hands after use, and avoid washing the area for the instructed time. Do not apply to breasts or broken skin unless specifically advised.

How it works

Estradiol replaces estrogen, helping reduce vasomotor and urogenital symptoms caused by estrogen deficiency after menopause or other estrogen-deficient states.

Common side effects

Possible effects include headache, breast pain, bloating, nausea, skin irritation, vaginal spotting, mood change, and weight change. Serious warning signs include breast lump, unusual vaginal bleeding, chest pain, shortness of breath, leg swelling, severe headache, vision changes, or jaundice.

Important information

Review use in unexplained vaginal bleeding, breast cancer, endometrial cancer risk, blood clots, stroke, heart disease, liver disease, pregnancy, breastfeeding, gallbladder disease, migraine, high triglycerides, and need for progestogen if uterus is present.