Ergotamine 1mg + Caffeine 100mg Tablets

Product Introduction

Ergotamine 1mg + Caffeine 100mg combines ergotamine with caffeine for acute migraine treatment for this older migraine-specific option treatment. Ergotamine narrows dilated cranial blood vessels and affects serotonin-related migraine pathways; caffeine improves absorption and may add vasoconstrictive effect. It is not for ordinary tension headache, chronic daily headache, migraine prevention, or frequent unsupervised use. Overuse can cause medication-overuse headache, ergot toxicity, dangerous blood-vessel narrowing, numbness or coldness of limbs, chest symptoms, high blood pressure, and reduced blood flow. It is also unsafe with strong CYP3A4 inhibitors such as some macrolide antibiotics, azole antifungals, HIV protease inhibitors, and certain antivirals because severe ergot toxicity can result.

How to use

Take Ergotamine 1mg + Caffeine 100mg only for migraine attacks as prescribed and within strict dose limits. Do not use daily or for prevention. Avoid triptans, other ergot medicines, and strong CYP3A4 inhibitors unless the prescriber confirms safe timing.

How it works

Ergotamine constricts cranial blood vessels and modulates serotonin receptors involved in migraine. Caffeine supports absorption and contributes mild vasoconstrictive activity.

Common side effects

Possible effects include nausea, vomiting, stomach pain, dizziness, weakness, tingling, muscle pain, and increased blood pressure. Serious warning signs include chest pain, severe limb pain, numb/cold fingers or toes, vision changes, confusion, severe abdominal pain, or signs of stroke.

Important information

Do not use in pregnancy. Review heart disease, stroke history, high blood pressure, circulation problems, liver/kidney disease, sepsis, smoking, breastfeeding, triptan use, other ergots, macrolides, azole antifungals, HIV medicines, and other CYP3A4 inhibitors.