Sumatriptan 85mg + Naproxen 500mg Tablets

Product Introduction

Sumatriptan 85mg + Naproxen 500mg combines sumatriptan, a triptan, with naproxen, an NSAID, for acute treatment of migraine with or without aura for this combination. Sumatriptan targets migraine-related 5-HT1B/1D pathways, while naproxen reduces prostaglandin-mediated inflammation and pain. The combination is for treating a migraine attack after it begins, not for daily prevention. It should be used only when the headache pattern is known to be migraine; sudden neurologic symptoms, worst-ever headache, head injury, fever with stiff neck, or a new headache pattern needs urgent assessment. This product carries both triptan cardiovascular cautions and NSAID risks.

How to use

Take Sumatriptan 85mg + Naproxen 500mg exactly as prescribed for an acute migraine attack. Do not combine with other NSAIDs, ergots, or triptans unless directed. Follow maximum daily dose limits.

How it works

Sumatriptan activates 5-HT1B/1D receptors to reduce migraine signaling. Naproxen inhibits prostaglandin synthesis to reduce inflammatory pain.

Common side effects

Possible effects include dizziness, drowsiness, nausea, indigestion, dry mouth, tingling, flushing, and chest/throat pressure. Serious concerns include heart attack, stroke, severe hypertension, arrhythmia, GI bleeding or ulcer, kidney injury, liver injury, serotonin syndrome, severe skin reaction, and allergy.

Important information

Review cardiovascular risk, stroke/TIA, blood pressure, GI ulcer/bleeding, kidney/liver disease, asthma with NSAID sensitivity, pregnancy, anticoagulants, antiplatelets, SSRIs/SNRIs, steroids, ACE inhibitors/ARBs, diuretics, lithium, methotrexate, MAOIs, triptans, and ergots.