Rifampin Rifampicin 150mg Tablets

Product Introduction

Rifampin Rifampicin 150mg is a rifamycin antibiotic used as part of combination treatment for tuberculosis and selected specialist infections for rifampicin/rifampin treatment. It blocks bacterial DNA-dependent RNA polymerase, stopping susceptible bacteria from making essential RNA and proteins. For tuberculosis, rifampicin should not be used alone because incomplete or irregular therapy can drive resistance and treatment failure. It is usually taken on an empty stomach unless the prescriber advises otherwise for stomach upset. A practical counseling point is harmless orange-red discoloration of urine, sweat, saliva, and tears, which can permanently stain soft contact lenses. The most important safety issue is interaction burden: rifampicin strongly induces drug-metabolizing enzymes and can reduce the effect of many medicines, including hormonal contraception, anticoagulants, antiretrovirals, antifungals, seizure medicines, transplant medicines, and some cardiac medicines.

How to use

Take Rifampin Rifampicin 150mg exactly as part of the prescribed regimen, commonly on an empty stomach. Do not miss doses or stop early. Use non-hormonal backup contraception if advised.

How it works

Rifampicin inhibits bacterial DNA-dependent RNA polymerase, blocking RNA synthesis and killing susceptible bacteria.

Common side effects

Possible effects include nausea, vomiting, abdominal pain, headache, dizziness, rash, fever, and orange-red body-fluid discoloration. Serious concerns include liver injury, severe allergy, low platelets, flu-like syndrome, kidney problems, and major drug interactions.

Important information

Review TB regimen, liver disease, alcohol use, HIV medicines, contraception, anticoagulants, antifungals, antiepileptics, transplant medicines, pregnancy, breastfeeding, baseline liver tests, and adherence plan.