
Prucalopride 1mg Tablets
SKU GME426
Product Introduction
Prucalopride 1mg is an oral selective 5-HT4 receptor agonist used for chronic constipation for prucalopride treatment, especially when lifestyle measures and laxatives have not provided adequate relief. It increases colonic motility by enhancing acetylcholine release in the gut, helping move stool through the intestine and increasing complete spontaneous bowel movements. Response should be judged by stool frequency, straining, bloating, abdominal discomfort, rescue-laxative need, and tolerability. Diarrhea can lead to dehydration in vulnerable patients.
How to use
Take Prucalopride 1mg as prescribed, with or without food. Keep hydration adequate, track bowel response, and do not use it for suspected bowel obstruction or severe unexplained abdominal symptoms.
How it works
Prucalopride selectively stimulates 5-HT4 receptors in the gut, increasing acetylcholine-mediated colonic motility and stool movement.
Common side effects
Possible effects include headache, nausea, diarrhea, abdominal pain, dizziness, vomiting, gas, fatigue, and decreased appetite. Serious concerns include dehydration from severe diarrhea, mood changes, suicidal thoughts, severe abdominal pain, and allergic reaction.
Important information
Review bowel obstruction symptoms, inflammatory bowel disease, unexplained rectal bleeding, severe abdominal pain, kidney disease, liver disease, depression history, suicidal thoughts, pregnancy, breastfeeding, and concurrent constipation medicines.
Uses
Chronic constipation when prucalopride therapy is prescribed, particularly after inadequate response to laxatives.
Benefits
Improves bowel motility and can increase complete bowel movements in selected patients with chronic constipation.
What is Prucalopride 1mg used for?
Prucalopride 1mg is used for chronic constipation for prucalopride treatment, often after laxatives have not worked well enough.
How does it help constipation?
It increases gut motility, helping stool move through the colon more effectively.
Can Prucalopride 1mg be used for bowel obstruction?
No. Severe pain, vomiting, distension, or suspected obstruction needs medical assessment before pro-motility treatment.
Why drink fluids?
Diarrhea can occur, and fluids help reduce dehydration risk if stools become loose.
When should treatment be reviewed?
No improvement after the planned review period, severe diarrhea, mood changes, or blood in stool should be reviewed.
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