Paracetamol (Acetaminophen) 1,000mg/100mL (10mg/mL) Infusion

Product Introduction

Paracetamol (Acetaminophen) 1,000mg/100mL IV Infusion is an intravenous paracetamol product used for short-term treatment of pain or fever when oral or rectal dosing is not practical. Paracetamol reduces pain and fever but does not treat inflammation like NSAIDs and does not treat the cause of fever. The main safety issue is total daily paracetamol exposure across all routes and products.

How to use

Paracetamol (Acetaminophen) 1,000mg/100mL IV Infusion is given by IV infusion by healthcare professionals. Dose and interval are calculated from age, weight, liver/kidney status, and other paracetamol exposure.

How it works

Paracetamol acts mainly in the central nervous system to reduce pain signaling and fever-regulating prostaglandin pathways.

Common side effects

Possible effects include nausea, vomiting, headache, low blood pressure during infusion, and infusion-site reactions. Serious concerns include liver injury from overdose, severe skin reaction, allergic reaction, and blood-count changes.

Important information

Review all paracetamol-containing products, liver disease, alcohol use, low body weight, malnutrition, fasting, kidney disease, pregnancy, breastfeeding, warfarin, enzyme-inducing medicines, and recent doses by any route.