Sodium Bicarbonate 8.4% w/v, 25mL Injection

Product Introduction

Sodium Bicarbonate 8.4% w/v Injection, 25mL is an intravenous alkalinizing solution used in monitored medical settings for metabolic acidosis or selected poisoning/urine-alkalinization situations for sodium bicarbonate treatment. It increases bicarbonate and raises blood or urine pH, helping buffer excess acid in specific clinical contexts such as severe renal disease, uncontrolled diabetes with acidosis, shock-related acidosis, severe dehydration, cardiac arrest protocols, or toxin elimination plans. Over-correction can cause metabolic alkalosis, high sodium, fluid overload, low potassium, low calcium symptoms, tissue injury from extravasation, and shifts in oxygen delivery.

How to use

Sodium Bicarbonate 8.4% w/v Injection, 25mL is given by trained healthcare professionals by IV route. Dose, dilution, infusion rate, and monitoring depend on acid-base status, electrolytes, kidney function, and clinical indication.

How it works

Sodium bicarbonate supplies bicarbonate ions that buffer hydrogen ions, increasing systemic or urinary pH when alkalinization is clinically needed.

Common side effects

Possible effects include vein irritation, fluid overload, swelling, high sodium, low potassium, low calcium symptoms, and alkalosis. Serious concerns include arrhythmia, tetany, seizures, tissue injury from extravasation, worsening CO2 burden, and severe fluid overload.

Important information

Review blood gas results, sodium/potassium/calcium, kidney function, heart failure, edema, hypertension, respiratory status, chloride depletion, vomiting, diuretic use, pregnancy, eclampsia risk, and infusion compatibility.