Rosuvastatin 5mg + Fenofibrate 160mg Tablets

Product Introduction

Rosuvastatin 5mg + Fenofibrate 160mg combines a statin with a fibrate for selected mixed dyslipidaemia, particularly when raised triglycerides accompany abnormal cholesterol. The need for both agents depends on the lipid pattern and overall risk.

How to use

Take the tablet with a meal, as food improves absorption of conventional fenofibrate formulations. Swallow with water and continue lipid testing. Do not add another statin or fibrate to the combination.

How it works

Rosuvastatin inhibits hepatic cholesterol synthesis and increases LDL removal. Fenofibrate activates PPAR-alpha, increasing breakdown of triglyceride-rich particles and modifying lipid transport.

Side effects

Stomach discomfort, nausea, headache, raised liver enzymes and muscle aches can occur. Severe muscle pain, dark urine, jaundice or persistent upper abdominal pain needs urgent assessment.

Important information

Combining a statin and fibrate increases muscle-injury risk, especially with renal impairment or untreated hypothyroidism. Active liver disease, gallbladder disease and kidney function matter. Anticoagulant effects may increase with fenofibrate.