Olmesartan Medoxomil 20mg + Hydrochlorothiazide 12.5mg Tablets

Product Introduction

Olmesartan Medoxomil 20mg + Hydrochlorothiazide 12.5mg combines an angiotensin-receptor blocker and a thiazide diuretic for high blood pressure. The complementary actions on blood vessels and salt balance help when combination therapy is needed.

How to use

Take in the morning, with or without food, to reduce night-time urination. Rise slowly if dizzy. Kidney function, sodium and potassium are monitored because the net electrolyte effect cannot be predicted from the two ingredients alone.

How it works

Olmesartan blocks angiotensin II at AT1 receptors. Hydrochlorothiazide increases sodium and water loss through the kidneys, reducing circulating volume and blood pressure.

Side effects

Dizziness, increased urination, dehydration and changes in sodium or potassium may occur. Severe weakness, palpitations, fainting or markedly reduced urination needs assessment.

Important information

Pregnancy, dehydration and significant kidney dysfunction are important risks. Hydrochlorothiazide can raise uric acid and worsen gout. Lithium and NSAIDs can interact. Persistent diarrhoea with weight loss warrants assessment of olmesartan-related enteropathy.