Nintedanib 150mg Soft Gelatin Capsules

Nintedanib is an antifibrotic tyrosine-kinase inhibitor used for idiopathic pulmonary fibrosis and selected progressive fibrosing interstitial lung diseases. It slows decline in lung function rather than reversing established scarring.
Take capsules intact with food, using the prescribed approximately 12-hour spacing when twice-daily treatment is selected. Do not open or crush them. Manage diarrhoea promptly using the clinic's hydration and antidiarrhoeal plan.
Inhibition of growth-factor receptor kinases involved in fibroblast activity reduces processes contributing to fibrotic lung remodelling.
Diarrhoea, nausea, vomiting, abdominal discomfort, weight loss and raised liver enzymes can occur.
Liver tests are needed before and during therapy. Bleeding risk, anticoagulants, gastrointestinal perforation risk and pregnancy require particular assessment.
Can slow lung-function decline in eligible fibrosing lung disease; it is not an immediate breathlessness reliever.
No. Its role is to slow progression rather than restore all damaged lung tissue.
Start the agreed supportive plan and contact the clinic if it persists or causes dehydration.
No. Resume the next scheduled dose rather than taking two together.
No. Oxygen and pulmonary rehabilitation may still be needed according to lung function.
Nintedanib can increase bleeding risk and the combined regimen needs assessment.
Dark urine, jaundice, loss of appetite or persistent nausea warrants prompt review.
No. Oncology and lung-fibrosis indications, dose schedules and formulations differ and cannot be exchanged automatically.
Lung-function testing, symptoms and the interstitial-lung-disease follow-up plan guide assessment.
Fibrosis: scar formation in tissue. Fibroblast: a cell involved in connective-tissue formation. FVC: forced vital capacity, a lung-function measurement., AR: Nintedanib كبسولات, FR: Nintedanib gélules, PT: Nintedanib cápsulas, ES: Nintedanib cápsulas, RU: Nintedanib капсулы, ID: Nintedanib kapsul, VI: Nintedanib viên nang, MS: Nintedanib kapsul, TL: Nintedanib kapsula, ZH-SG: Nintedanib 胶囊
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Nintedanib 150mg Soft Gelatin Capsules