Dexmedetomidine 50mcg/0.5mL Injection

Dexmedetomidine 50mcg/0.5mL Injection is an alpha-2 adrenergic sedative used for selected intensive-care or procedural sedation. Sedation can resemble sleep with some arousability, but continuous clinical monitoring remains essential.
Administer by a controlled intravenous infusion with the dilution appropriate to the supplied formulation. A trained team adjusts the rate to sedation and haemodynamic response; rapid bolus administration is inappropriate.
Alpha-2 receptor activation in the central nervous system reduces noradrenaline release and sympathetic activity, producing sedation and some analgesic-sparing effects.
Bradycardia, low blood pressure, dry mouth and occasionally transient hypertension may occur.
Conduction disease, reduced circulating volume and other sedatives can increase risk. Monitor breathing, circulation and sedation depth; prolonged treatment can produce withdrawal symptoms on abrupt cessation.
Provides titratable sedation and can reduce requirements for some other sedative or analgesic medicines.
Some arousability is characteristic and does not necessarily mean sedation has failed.
No. Airway and respiratory monitoring remain necessary, especially with other sedatives.
Reduced sympathetic activity can cause clinically significant bradycardia.
No. Concentrated and ready-to-use preparations have different dilution requirements.
Not generally. Anaesthesia and analgesia needs depend on the procedure.
Transient hypertension can occur, particularly with rapid or loading administration.
Yes. Sedative and haemodynamic effects can be additive.
Agitation, tachycardia or hypertension may occur; discontinuation should be planned.
Alpha-2 agonist: a medicine that stimulates inhibitory adrenergic receptors. Bradycardia: an unusually slow heart rate. Sedation: medically reduced awareness and arousal.; AR: Dexmedetomidine 50mcg/0.5mL حقن; FR: Dexmedetomidine 50mcg/0.5mL injection; PT: Dexmedetomidine 50mcg/0.5mL injeção; ES: Dexmedetomidine 50mcg/0.5mL inyección; RU: Dexmedetomidine 50mcg/0.5mL инъекция; ID: Dexmedetomidine 50mcg/0.5mL injeksi; VI: Dexmedetomidine 50mcg/0.5mL thuốc tiêm; MS: Dexmedetomidine 50mcg/0.5mL suntikan; TL: Dexmedetomidine 50mcg/0.5mL iniksyon; ZH-SG: Dexmedetomidine 50mcg/0.5mL 注射剂
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Dexmedetomidine 50mcg/0.5mL Injection