Cefazolin 500mg Injection

Product Introduction

Cefazolin Sodium 500mg is an injectable first-generation cephalosporin antibiotic used to treat susceptible bacterial infections and to prevent infection around surgery. It is commonly used for selected skin and soft-tissue infections, bone and joint infections, urinary infections, respiratory infections, biliary infections, bloodstream infection, endocarditis, and perioperative prophylaxis according to the clinical plan. Cefazolin kills bacteria by interfering with bacterial cell-wall formation. It does not treat viral infections. Allergy history is important, especially previous severe penicillin or cephalosporin reactions.

How to use

Cefazolin 500mg is reconstituted and given by trained healthcare staff by the prescribed IV or IM route. Doses should be given at the scheduled interval. Cultures, kidney function, allergy symptoms, and infection response may be monitored.

How it works

Cefazolin blocks bacterial cell-wall synthesis by binding penicillin-binding proteins. Susceptible bacteria lose cell-wall integrity and die.

Common side effects

Possible effects include injection-site pain, diarrhoea, nausea, vomiting, rash, itching, fever, and changes in liver or blood tests. Serious concerns include anaphylaxis, severe skin reactions, antibiotic-associated colitis, seizures with excessive levels, and kidney-related accumulation.

Important information

Tell the clinician about penicillin or cephalosporin allergy, kidney disease, seizure history, bowel disease, anticoagulants, pregnancy, breastfeeding, and recent antibiotic-associated diarrhoea. Use only for proven or strongly suspected bacterial infection or surgical prophylaxis.