Benzyl Penicillin 500000IU Injection

Product Introduction

Benzyl Penicillin 500000 IU is an injectable penicillin G antibiotic used for serious infections caused by susceptible bacteria. Benzyl penicillin reaches active blood levels quickly after appropriate parenteral administration and is used in hospital or supervised settings for infections where rapid penicillin therapy is needed. Depending on local guidance and culture results, it may be used for susceptible streptococcal infections, meningococcal disease, pneumococcal infections, severe soft-tissue infections, endocarditis, congenital or neurosyphilis regimens, and other invasive infections. It is not a substitute for long-acting benzathine penicillin when that depot formulation is specifically required. Allergy history must be reviewed carefully because penicillin can cause anaphylaxis.

How to use

Benzyl Penicillin 500000 IU is administered by trained healthcare staff by the prescribed parenteral route after correct reconstitution and dilution. Do not self-use. Cultures, kidney function, electrolytes, clinical response, and allergy symptoms may need monitoring during treatment.

How it works

Benzyl penicillin interferes with bacterial cell-wall construction by binding penicillin-binding proteins. Susceptible bacteria lose cell-wall integrity and die.

Common side effects

Possible effects include injection-site pain, nausea, diarrhoea, rash, fever, and changes in blood counts or electrolytes. Serious risks include anaphylaxis, severe skin reactions, seizure risk with very high levels, kidney-related dosing problems, and antibiotic-associated colitis.

Important information

Tell the clinician about penicillin or cephalosporin allergy, asthma, kidney disease, seizure disorder, heart failure, sodium/potassium restrictions, pregnancy, breastfeeding, anticoagulants, methotrexate, probenecid, and other antibiotics. Use only for bacterial infections likely to be susceptible.