Amantadine 193mg ER Tablets$65.00
1–9 boxes
$65.00 each
10–24 boxes
8% off
25+ boxes
10% off
Amantadine 193mg ER Tablets
SKU GME1053Product Introduction
Amantadine 193mg is an extended-release antiparkinsonian medicine used for Parkinson's disease and selected medicine-induced movement symptoms. This prolonged-release tablet family is distinct from conventional tablets and from bedtime extended-release capsules.
How to use
Take the extended-release tablet in the morning, with or without food. Swallow it whole; do not chew, crush or divide it. Kidney impairment can require less frequent dosing. It is not interchangeable milligram for milligram with other amantadine formulations.
How it works
Amantadine modifies dopamine signalling and blocks NMDA-type glutamate receptors. These actions can improve motor symptoms and reduce excessive excitatory signalling in movement-control pathways.
Side effects
Dizziness, insomnia, nausea, dry mouth, ankle swelling and a mottled purple skin pattern can occur. Hallucinations, severe confusion, fainting or new compulsive behaviour need prompt assessment.
Important information
Drug accumulation is more likely with kidney impairment and in older adults. Tell your doctor about seizures, heart failure, hallucinations or glaucoma. Alcohol and sedating medicines can worsen confusion or dizziness. Sudden withdrawal may cause severe stiffness, fever or mental-state changes.
Uses
- Parkinson's disease and selected drug-induced extrapyramidal movement symptoms.
Benefits
May ease movement-related disability as part of a Parkinson treatment plan. The response and tolerability determine whether it is useful alongside other motor-symptom medicines.
Can a mottled purple skin pattern be medicine-related?
Yes. Livedo reticularis is a recognised effect of amantadine, sometimes with ankle swelling. Report a new persistent pattern, especially if swelling is also increasing.
What behaviour changes should a family member watch for?
New compulsive gambling, shopping, eating or sexual urges can occur. These changes may be easier for someone close to the patient to recognise.
Why might the dosing interval change in kidney disease?
The kidneys remove most of the medicine. A longer interval or lower amount may prevent accumulation, hallucinations and confusion.
Can I switch this extended-release tablet to conventional amantadine or a different long-acting formulation?
No. Conventional and extended-release products differ in drug delivery and sometimes in how the strength is expressed. A planned conversion is needed.
Parkinsonism: slowness, stiffness or tremor related to dopamine-system dysfunction; NMDA receptor: a glutamate receptor involved in excitatory nerve signalling; Livedo reticularis: a mottled net-like skin pattern; Extrapyramidal symptoms: medicine-related movement abnormalities; Impulse-control disorder: difficulty resisting harmful repetitive urges; AR: Amantadine 193mg أقراص ممتدة التحرر; FR: Amantadine 193mg comprimés à libération prolongée; PT: Amantadine 193mg comprimidos de libertação prolongada; ES: Amantadine 193mg comprimidos de liberación prolongada; RU: Amantadine 193mg таблетки пролонгированного высвобождения; ID: Amantadine 193mg tablet lepas lambat; VI: Amantadine 193mg viên nén giải phóng kéo dài; MS: Amantadine 193mg tablet pelepasan berpanjangan; TL: Amantadine 193mg tabletang may pinalawig na paglabas; ZH-SG: Amantadine 193mg 缓释片