Adenosine 6mg/2mL (3mg/mL) Injection

Product Introduction

Adenosine Injection 2mL is an intravenous anti-arrhythmic medicine used in monitored medical settings. Adenosine is used for rapid termination or diagnostic clarification of certain supraventricular tachycardias where the abnormal rhythm depends on the atrioventricular node. Adenosine is not a daily rhythm-control tablet and should not be used outside a setting where clinicians can monitor heart rhythm, blood pressure, breathing, and response. It can briefly cause flushing, chest pressure, breathlessness, dizziness, nausea, a sense of impending discomfort, or transient pauses/blocks in heart rhythm. Caffeine, theophylline, dipyridamole, asthma or bronchospasm history, heart block, pacemaker status, seizure history, and unstable heart disease all matter for deciding whether adenosine treatment.

How to use

Adenosine Injection 2mL is given by a doctor or trained healthcare professional as a rapid intravenous injection or infusion according to the indication and local protocol. Continuous ECG monitoring and resuscitation equipment should be available. The line is usually flushed rapidly after administration because adenosine has an extremely short duration of action.

How it works

Adenosine briefly slows conduction through the atrioventricular node. In AV-node-dependent supraventricular tachycardia, this can interrupt the re-entry circuit and restore a normal rhythm. Its short half-life explains both the rapid effect and the brief nature of many side effects.

Common side effects

Common short-lived effects include flushing, warmth, chest pressure, breathlessness, dizziness, nausea, headache, throat or jaw discomfort, sweating, and a feeling of anxiety. Serious risks include significant low blood pressure, bronchospasm, high-grade AV block, prolonged pause, ventricular arrhythmias, seizure, and cardiac arrest in susceptible patients.

Important information

Use only with ECG monitoring and emergency support. Adenosine may be unsuitable in second- or third-degree AV block, sick sinus syndrome without a functioning pacemaker, active bronchospasm or asthma, unstable angina, severe hypotension, or certain seizure-risk situations. Caffeine and methylxanthines can reduce effect, while dipyridamole may increase sensitivity.